Imaam Shafi’ee (rahimahullaah) said:

”The hour will not be established (i.e. the Day of Judgement) until knowledge becomes ignorance  and ignorance becomes knowledge”

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[Source: Quoted by Shaikh Abdullaah Al-Bukhaari in Maqaalaat Ash-Shar-iyyah

page: 23; and the original source is in Musannaf Ibn Abee Shaybah 15/176]